Relationships of physical fitness, obesity indices and sex hormone binding globulin with lipid and glucose metabolism in premenopausal obese women / 体力科学

The purpose of the present study was to investigate the relationships of physical fitness, body mass index (BMI), waist-hip ratio (WHR) and sex hormone binding globulin (SHBG) with lipid and glucose metabolism in premenopausal obese women aged 32 to 49 yrs (n=24) . WHR was significantly correlated with HDL-C, HDL<SUB>2</SUB>-C and Apo B, but not correlated with BMI %fat, maximal oxygen uptake (VO<SUB>2</SUB>max), triglyceride (TG), very low density lipoprotein % fat, and Apo A 1. VO<SUB>2</SUB>max/kg was significantly associated with BMI, TG, HDL-C, HDL<SUB>2</SUB>-C, Apo Al, low density lipoprotein (LDL), SHBG, glucose metabolism at rest and during oral glucose tolerance test (OGTT) . The SHBG was strongly correlated with HDL-C, HDL<SUB>2</SUB>-C and Apo A 1. In multiple regression analysis, it was observed that SHBG was one of the independ-ent predictor of HDL-C, HDL<SUB>2</SUB>-C and Apo Al, that VO<SUB>2</SUB>max was good predictor of LDL, Apo B and glucose metabolism at rest and during OGTT, and that BMI was one of the determinat of TG and VLDL. From these results, we concluded that lipid metabolism was independently associated with aerobic work capacity, SHBG, BMI as well as WHR, and that glucose metabolism was independently associated with aerobic work capacity.

Reversible Cerebral Damage Following Bilateral Ascending Aorta-Internal Carotid Artery Bypass Operation for Aortitis Syndrome: A Case Report / 日本心臓血管外科学会雑誌

Aortitis is an inflammatory arteriopathy that often progresses to obliteration of multiple large arteries. Surgical treatment for obstructive lesions due to aortitis syndrome therefore is difficult in many cases. The patient was a 23-year-old female who at the age of 19 had been diagnosed as aortitis syndrome with cerebral vessel involvement, and she subsequently received steroids. She increasingly experienced syncopal attacks, and was indicated for surgical treatment. Angiography revealed obstruction of the left common carotid and left subclavian arteries, and severe stenosis of the right common carotid and right vertebral arteries. She underwent bilateral ascending aorta-carotid artery bypass operation with 7mm ring-supported EPTFE grafts. After the operation she developed clinical signs of temporary brain damage due to hyperperfusion syndrome, but she now completely recovered and maintains a good clinical condition.